Researchershave notice two drugsalready in various stage of purpose and human clinical trial that seem to prevent all neurodegenerative diseases in computer mouse . Published in the journalBrain , the research could be a major find in forbid the devastating diseases from progressing in humanity .
When brain cells are taint with a virus , the pathogen co - opts the cell to produce its own viral proteins , which start out to ramp up up within the cell . In purchase order to fight this and keep the bed cover of the virus , the cell reacts by kibosh all protein product . In many neurodegenerative diseases , a alike situation pass , in which defective proteins are over - produced in the wit cells and the brain reacts in a very alike way , but for much more prolonged periods .
trouble start to rise because the nous cells halt protein production for such a long menstruation of time that the brains cells effectively starve themselves and start dying . When this spreads to neurons , it can then lead to the familiar symptom of computer memory loss , movement impairment , and even death in severe types of neurodegenerative disease .
In 2013 , the same team of researchersfound a compoundthat forestall the Einstein cells from overreacting and shutting down all protein production , which prevented the brain cells from die . Yet there was a catch : the atom also damage the pancreas . And so they have since reverse to other drug to see if they can find others that achieve a interchangeable issue .
After screening over 1,000 unlike drugs already in existence , they issue forth acrosstwo that seemed to have the hope gist . One of these , known as trazodone , is already used clinically to treat patients with depression , while the 2nd , called DBM , is of course found in small amount in licorice and is presently undergo trial run to see if it can effectively treat cancer .
This is promising news show , as since the drug have already been or are in the outgrowth of being tested on humans , it should make the appendage of proceeding to clinical trials much easy . While the researchers accent that the drugs are not a cure , they could prevent the disease progress , radically altering how we treat them .
