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Former U.S. Supreme Court Justice Sandra Day O’Connor — the first fair sex appointed to the U.S. eminent motor inn — announced that she had been name with dementia .
" Some time ago , doctors diagnosed me with the beginning stages of dementia , in all likelihood Alzheimer ’s disease , " O’Conner wrote in apublic letterdated today ( Oct. 23 ) .
Former U.S. Supreme Court Justice Sandra Day O’Connor
Alzheimer ’s disease is a form of dementia , but how do doctors distinguish between the ill-famed disease and other word form of dementedness ? [ 6 Big Mysteries of Alzheimer ’s Disease ]
Dementia is a full general termthat embrace any circumstance that ’s tie in to the loss of cognitive functioning — such as thinking , remembering and reasoning — and that involve a person ’s casual operation , according to theNational Institute on Aging .
Everyone suffer brain cellphone or nerve cell as they mature . But a person with dementedness suffer far more neuron and connector to other neurons thatallow important signals to travel through the brain . In its various stage , dementia can strike a person ’s memory , linguistic communication , ocular perception , problem - solving skill , self - management and power to pay attending .
" Alzheimer ’s disease is the most common form of dementedness among older people , " enounce Dr. Rawan Tarawneh , a brain doctor at The Ohio State University Wexner Medical Center , who is not imply with O’Connor ’s case .
Typically , the first symptom of the disease are difficulty with light - term memory , such as having trouble remembering recent conversation , events or people ’s public figure , Tarawneh recite Live Science . Other early symptom can admit having trouble finding Word during conversations or reduced job - figure out power , such as in managing finances . Depression and red ink of interestin some activity are also plebeian , she aver .
As Alzheimer ’s disease progress , people can have more trouble communicating , get lost in position they know well and have poor judgement in societal place , Tarawneh say . People can also experience behavioral change — such as agitation , excitability , episode of wandering , hallucinations and delusions — as the disease progresses , she say . " In the most stern cases , a person with Alzheimer ’s disease may ask help with simple activity , such as walking , feeding or dress themselves , " she said .
Buta stack of these symptoms are also common in other types of dementia . So , what makes different dementedness , well , different ? It comes down to what ’s happening in the mentality .
Alzheimer’s or another form of dementia?
A trademark of Alzheimer ’s disease that distinguishes it from other forms of dementedness is an increment in a character of protein called amyloid in the brainiac . One of the first biologic changes to occur in the brain of a person with Alzheimer ’s is thebuildup of clumps of these protein , visit amyloid plaques , between neurons , which hinders their function . Another characteristic of Alzheimer ’s disease is abuildup of a different protein , call tau . The buildup of both type of protein leads to neurodegeneration , or brain - cell decease .
But unlike amyloid plaques , tau buildup and neurodegeneration are n’t alone to Alzheimer ’s disease ; they can also go on in other kind of dementia , said Rebecca Edelmayer , the managing director of scientific booking at the Alzheimer ’s Association . This is why " it can be hard , sometimes , to determine [ what form of dementedness a person has ] based on cognitive testing and symptom alone , " she said .
Indeed , dementedness diagnosing remain a moment shivering . There are " a number of people who get told they have Alzheimer ’s but they do n’t actually have it , " Edelmayer tell Live Science .
To make matters more confusing , many multitude do n’t have " pure " Alzheimer ’s disease or a " virgin " other human body of dementia , but rather , a mixture of different dementias , Edelmayer said . These can include vascular dementia , which affects the descent vessels in the psyche , andLewy dead body dementia , which is qualify by the buildup of yet another type of protein in the head .
" What the scientific field of operations is trying to do now is to produce other ways to differentially name individual ' dementedness using biomarkers , " Edelmayer said . Biomarkers are biological change in the brain , such as an increment in amyloid brass , that can find the presence of a disease . Some of these biomarkers appear in people as early on as 10 to 20 years before the soul first shows symptoms of dementia , Edelmayer added .
Making the right diagnosing is important , because " all of these different type of dementia are characterize by dissimilar biological changes in the genius , " Edelmayer said . So , if doctors do it exactly what ’s going on in the brain , they can tailor-make more - specific treatment to the disease .
Originally release onLive Science .
